Diffusion MRI is a powerful
tool to characterize tissue micro structure and to identify and differentiate
disease processes. Diffusion is a process describing the motion of water
molecules in biological tissue. Diffusion MRI makes use of sequences developed
to reveal differences in tissue characteristices with the parameters mean
diffusivity D and the anisotropy FA.
Diffusion MR imaging has demonstrated its value for the early detection of
stroke. Diffusion imaging also promises to further our understanding of brain
disorders and abnormalities such as tumors, multiple sclerosis, and
Advanced mathematical algorithms can be applied to reveal the connectivity of
white matter fibres from multi-directional diffusion tensor measurements. Since
the diffusion across fibres is restricted and almost free along the fibres, this
property can be used to compute three-dimensional representations of fibre
structures. The image below is an example to reveal the directional
characteristics of the corpus callosum.